Takeaway
Twenty-five consensus statements addressing the pathophysiology of impaired cerebrovascular autoregulation (CA) and its effect on cerebral perfusion pressure (CPP) targets and outcome resulted from the Delphi procedure.
Why this matters
There is a lack of a gold standard and prospective data regarding secondary brain injury risks, impact on care and outcomes of implementation of CA-guided management in severe traumatic brain injury (TBI) treatment, leading to uncertainty.
The identification of multiple consensus statements addressing CA-guided management of patients with severe TBI highlights the need for prospective clinical studies examining the feasibility, safety and efficacy of this methodology in this particular cohort.